Victim identifed as Christopher Kellar, 21, of Portsmouth, NH.
Boston Police report a man was fatally stabbed at the Hotel Indigo, 280 Friend St., around 11:25 p.m. on Saturday.
Ren A. Rodgers, 23, of Hollis, NH was arrested on a charge of murder, police say.
Live Boston reports Rodgers may have stabbed his girlfriend's brother during a heated argument.
This is the second murder at a Boston hotel this month; on Feb. 4, a 17-year-old was shot to death at the Hyatt Regency on Avenue de Lafayette downtown.
Boston murders in 2021.